Dr. B Ravi Shankar
ackground andobjectives: This study, conducted in South India, aims to investigate the occurrence of acute pancreatitis as a complication of dengue fever and to determine the mortality rate and risk factors in patients who developed acute pancreatitis. Subjects and Methods: By analyzing medical records from Yashoda Hospital, Secunderabad, the incidence, mortality rate, and associated risk factors of acute pancreatitis in dengue patients were assessed. The diagnosis of acute pancreatitis was based on the revised Atlanta criteria. Statistical analyses included Chi-square and Fisher’s exact tests, with a significance level set at p < 0.05. Results: A total of 702 dengue patients with an average age of 28.7 years were included. The severity of infection was categorized as dengue fever, dengue hemorrhagic fever, and dengue shock syndrome in 42.16%, 55.55%, and 2.28% of cases, respectively. Common dengue symptoms were fever, chills, weakness, vomiting, and body pain, while laboratory markers such as thrombocytopenia, leukopenia, elevated transaminase levels (SGPT, SGOT), and low serum albumin levels indicated complications. Conclusion: Acute pancreatitis was identified in 41 (5.8%) dengue patients, with a mortality rate of 1.7% in the overall population and 7.31% in those with acute pancreatitis. Notably, individuals aged 51 years or older were at higher risk for acute pancreatitis. In conclusion, this study suggests that acute pancreatitis is an underreported complication of dengue, and its occurrence significantly correlate with increased mortality.
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