Revista estadounidense de administración avanzada de fármacos Acceso abierto

Abstracto

Poly (Ethylene-Co-Vinyl Acetate) Blends for Controlled Drug Release

Magda A AkL, Abd-Elrazek HM and Abdel Bary EM

Ethylene vinyl acetate copolymer (EVA) was blended with polyvinyl acetate polymer (PVAc) to form EVA/PVAc blends. Paracetamol was used as a drug model in the investigated blends. Different weight ratios of the two polymers in the blend were investigated, these are (100/0, 80/20 50/50, 20/80, 0/100 w/w EVA/PVAc). The concentration of the drug was kept constant. The micro structure, as well as crystallinity and chemical composition of these blends were investigated. The scanning electron microscopy (SEM) has been conducted for blends before and after release. Crystallization behavior of EVA was investigated as well as X-ray diffraction (XRD) of the blends. Besides FTIR spectrum of the samples and equilibrium swelling and deswelling of the blends has been carried out.

Descargo de responsabilidad: este resumen se tradujo utilizando herramientas de inteligencia artificial y aún no ha sido revisado ni verificado