Revista de VIH y virus retro Acceso abierto

Abstracto

Risk Factors of the Transmission of the HIV, Hepatitis B and C and Syphilis among Blood Donors at the Saint Luc General Hospital of Kisantu, Democratic Republic of Congo

Lupande Mwenebitu David, Busa Mabaya Gael, Pululu Christian, Mukuku Olivier, Phoba Marie-France and Lunguya Metila Octavie

Introduction The blood donation is an altruistic but dangerous act. The Human Immunodeficiency Virus (HIV), the Hepatitis B Virus (HBV), the Hepatitis C Virus (HCV) and Syphilis must be subjected to a regular epidemiological monitoring in order to reduce the infectious risk of their transmission. This study aims to determine the epidemiological and serological profile of blood donors of to the Saint Luc General Hospital of KISANTU. Methods This retrospective study from November 2010 to November 2014 conducted among blood donors at the Saint Luc Hospital in KISANTU. For the screening, only the rapid tests were used (Determine HIV 1 and 2, Determine HBsAg, HCV One Step and RPR). Statistical analysis was performed using SPSS 21.0, the chi-square test or Fisher exact test (when recommended) was used to find a relationship between epidemiological parameters and seropositivity to tested antigens. The significance level was set at p <0.05. Results A total of 7434 blood donors were collected including 6787 male (91.30%) and 647 female (8.70%). The majority of donors were between 26-35 years of age (39.52%); the mean age was 31.1 ± 9.1 years. The age group of 36-45 years was a protective factor for HBV (OR <1, p <0.05), seroprevalence of HIV, HCV and syphilis were 2.93%, 1.86% and 0.66%. Conclusions A high prevalence of Hbs antigen has been found in our series. Epidemiological surveillance must be strengthened within the national blood transfusion program in DR Congo in order to reduce the infectious risks that are transmitted during blood transfusions.