Revista estadounidense de administración avanzada de fármacos Acceso abierto

Abstracto

Synthesis and Total Phenol Content of New Resveratrol Derivative

Essam F.A. Al-Jumaily, Ghada S. Hamid and Karima F. Ali

This study was conducted with the aim to extract and purify a polyphenolic compound “Resveratrol” from the skin of black grapes Vitisvinifera cultivated in Iraq and synthesis new derivative. Chemical investigations and tests for the identifications carried out for the qualification of extracted crystals yield include: general tests for polyphenoles, aromatic unsaturated compounds, spectrophotometric scanning for λmax screening, High Performance Liquid Chromatography (HPLC) comparable with standard and Fourier Transform Infrared (FTIR) to observed groups of compound. Synthesis new derivatives from purified resveratrol were done throughout series of reactions accompanied with FTIR for each derivative. The derivative is (E)-5-(4-(3, 4, 5-trihydroxybenzoyl) oxy) styryl)-1, 3-phenylene bis (3, 4, 5 tri hydroxyl benzoate). The IR spectroscopy result confirms the presence of functional groups in the proposed compounds.