Marta Sandini, Nicolò Tamini, Pietro Allegranza, Cammillo Talei Franzesi, Davide Ippolito, Luca Gianotti
Introduction The safety and the protective role of stenting the pancreato-jejunal anastomosis on the occurrence of pancreatic fistula is debated. Aim of this study was to evaluate the outcome of patients who received internal stenting during pancreatoduodenectomy and to review the literature on the related complications. Methods From 2007 to 2014 we performed 207 pancreatoduodenectomies with endto- side duct-to-mucosa pancreato-jejunal anastomosis. We retrospectively analyzed the outcome of 38 high-risk patients with an internal stent through the pancreato-jejunal anastomosis. The occurrence and severity of pancreatic fistula were defined according to International Study Group of Pancreatic Fistula classification. We evaluated the fate and complications of the stents by radiological and clinical follow-up. A literature review was performed through web-search. Results No patients had stent-related symptoms or complications. Seven patients (18.4%) developed clinically relevant pancreatic fistula. We had a mean of 1.9±0.9 (SD) postoperative imaging exams for 33 patients. The median time of follow-up was 3 months (range 1-62). The stent was no longer visible in 17 patients (51.5%); in 8 cases (24.2%) it was in the pancreatic duct, in 7 (21.2%) migrated in the jejunal limb and in 1 patient into the colon. By literature review we retrieved 13 papers reporting on long-term outcomes of internal pancreato-jejunal stenting. Discussion Internal stenting does not seem to be associated with major long-term morbidity, but the short follow-up does not allow definitive judgment on the fate of the stents still in place or dislocated into the jejunal limb. Literature describes a low rate of complications, mainly hepato-biliary infections due to stent migration.
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