Dermatología Clínica Pediátrica Acceso abierto

Abstracto

Wound Care & Regenerative Medicine 2019: Current trends and challenges in 3D/4D biofabrication using multifunctional smart biomaterials and nanomaterials - Luciano Paulino Silva - Brazil University of Brasília

Luciano Paulino Silva

Bio fabrication is a multidisciplinary research field combining principles from engineering, biology and material sciences through the application of multiple manufacturing processes to create bio-objects that mimic the architecture of living systems. Indeed, it debuted in scientific and technological scenarios as potential strategies for tissue engineering, regenerative medicine and related areas aiming the production of organoid models for drug screening and cosmetics evaluation, tissues for reconstruction and organs for transplantation. However, now other areas like agriculture and veterinary as well as the food industry can benefit from this exciting field. Probably, hydrogels represent the most essential building blocks for production of scaffolds and cells entrapment aiming bio fabrication. Interestingly, natural polymers derived from agricultural, forestry and livestock products and by-products are the most largely used raw materials for production of hydrogels useful for bio fabrication purposes since they are typically abundant, inexpensive, renewable, biodegradable, and biocompatible and considered appropriate from chemical, structural and mechanical standpoints.