Chandra Prakash K. and I. J. Kuppast
The present study aimed to evaluate the CNS activities of the alcoholic and aqueous extracts of Cardiospermum halicacabum and Dodonea viscosa, family sapindaceae in various experimental models described as pentobarbitone induced sleeping time, locomotor activity and motor coordination. The extracts were subjected for acute toxicity studies and found no mortality upto the dose of 2000mg/kg bodyweight hence 1/5th and 1/10th of the dose tested were used as the test dose and found exhibiting dose dependant CNS activities with all the experimental models. The phytochemical studies revealed the presence of various flavonoids, tannins, triterpenoids and saponins which might have contributed for the said activities.
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