diario americano de Administración de Medicamentos y Terapéutica Acceso abierto

Abstracto

Correlation between folic acid and homocysteine level in patients with type 2 diabetes

Mimoza Bafqari Bakiji

This study analyzes the association between folic acid and homocysteine level in patients with type 2 diabetes. In this study were included 27 diabetic patients and 24 non-diabetic patients. Diabetic patients had a significant increase of the value of glucose (p<0.0001) and the value of  HbA1c (p<0.0001).  Significant difference is also observed in the concentration of homocysteine between the two groups of patients included in the study (p=0.0280), while no significant difference is observed with respect to folic acid concentration (p=0.3324). The results showed homocysteine level as a risk factor for many other disorders. While in diabetic patients, compared to normal healthy patients without diabetes, folic acid levels do not show a significant change. Our findings suggest that in patients with type 2 diabetes we have an increase in the level of homocysteine, respectively in addition to treatment with appropriate therapy insulin and metformin. Appropriate clinical condition for the development and progression of various disorders. Therefore, accurate treatment and evaluation of folic acid and homocysteine levels are key indicators for various related diseases in any patient affected by type 2 diabetes.